IGF1 and acromegaly: Thus, acromegalic patients are characterized by a higher Framingham risk score than normal subjects, caused by high blood pressure, dysglycemia, and hyperlipidemia (12).To define the biochemical control of acromegaly, the Endocrine Society suggests the goal of a random GH less than 1 μg/L and normal IGF-1 for age and sex (2).