GH1 and pituitary gland adenoma: After NS, 11 patients were in remission (68.8%) whereas 5 patients (31.2%) required adjuvant therapy (3 DA, 1 SSA, 1 DA+SSA), achieving an adequate disease control.Two patients underwent biopsy of the pituitary lesion in another center, confirming the diagnosis of pituitary adenoma with GH positivity at IHC.