HLA-C and neoplasm: IFN‐γ produced by Th1 cells, referred to as an important antitumor cytokine, can enhance the antitumor response through various ways, such as promoting the activation of CTLs, upregulating the expression of MHC molecules on DCs to improve the efficiency of antigen presentation, promoting the generation of M1‐like macrophages, inhibiting the suppressive microenvironment, and mediating the formation of the early vascular system in tumor tissue.25, 26