MMP9 and neoplasm: The mean r24 was 0.27, nighttime restfulness (proportion of activity in bed that falls below the median out of bed activity) was 97.21%, daytime sedentariness (proportion of activity out of bed that is below the median in bed activity) was 6.59%, mean sleep time was 386.94 min, sleep efficiency was 89%, and wake after sleep onset was 13 min.Uncoordinated rest-activity rhythm, such as poor inter-daily stability, was associated with elevated markers VEGF, TGF-beta, and MMP-9 (associated with angiogenesis, immunosuppression, epithelial-mesenchymal transition, tumour invasion, and metastasis).