found that Let-7i-5p rescued a range of tumor suppressive effects of HDAC6, while the ectopic expression of a Let-7i-5p antisense inhibitor (AS-Let-7i-5p) inhibited tumor cell proliferation, induced apoptosis, and prevented migration under chemotactic stimulation, revealing that Let-7i-5p promotes HCC (20). The gene discussed is HDAC6; the disease is neoplasm.