According to Ravindresh Chhabra’s study, Let-7i-5p overexpression and SOX2 silencing could both decrease the number of spheroids formed in the cervical cancer cell lines HeLa and CaSki, while HMGA2 and SOX2 expression were significantly reduced in CaSki following Let-7i-5p overexpression (39). Here, SOX2 is linked to cervical carcinoma.