We hypothesize that through the inhibition of CYP2B6, CYP2C9, CYP2C9, CYP2C19, and CYP3A4, Schisandra chinensis preparations increased the concentration and side effects of bupropion (thrombocytopenia (Altintas et al., 2013) and generalized arthralgia (Ornetti et al., 2004)), amitriptyline (delirium (King and Ashraf, 2018)), and fluoxetine (dysuria (Fluoxetine Side Effects, 2023)). The gene discussed is CYP2B6; the disease is delirium.