CAV2 and cancer: Studies have found that the expression of Cav-2 is upregulated in MCF-7 cells (Hnasko and Lisanti, 2003), while Shatseva et al. (2011) reported that miR-199a-3p can promote cell proliferation by inhibiting the expression of Cav-2, suggesting that Cav-2 plays a role in cancer inhibition.