TLR4 and infection: Another mechanism that activates hemocytes in defense against infections and bacteria is driven by the Imd and Toll pathways in which Spaetzle (Spz), the ligand of the Toll receptor, initiates a humoral response in the FB that causes the secretion of antimicrobial peptides, including Diptericin (Dpt) and Drosomycin (Drs) (Lemaitre and Hoffmann, 2007).