PINK1 and muscular dystrophy: Recent studies show that UA initiates mitophagy via stabilizing PINK1 and activates autophagy, thereby prolonging lifespan in normal C. elegans and improving muscle function in C. elegans and rodents with muscular dystrophy (D'Amico et al., 2021; Luan et al., 2021; Ryu et al., 2016).