To determine DNAJB1 roles in CSE‐induced PMVECs and confirm whether miR‐23a‐3p mediated emphysema progression by regulating DNAJB1, PMVECs were transfected with sh‐DNAJB1 and miR‐23a‐3p inhibitors. The gene discussed is DNAJB1; the disease is pulmonary emphysema.