IL34 and early-onset autosomal dominant Alzheimer disease: An intronic variant of IL34 (rs78927322, chr16:70,636,538 C/G, not tested in our analysis due to low MAF), located 22 Kb upstream from the locus that we defined, had been previously associated with hippocampal volume in Alzheimer’s disease patients (Alzheimer Disease Neuroimaging Initiative (ADNI) cohort) [67].