Interestingly, these processes were not disrupted by deleting CCDC25 (Figure S7I, Supporting Information), a known NETs‐DNA sensor in breast cancer.[8]CCDC25 depletion only showed a modest effect on NETs‐mediated HCC cell chemotaxis, likely due to its lower expression in HCC than in breast cancer (Figure S7J,K, Supporting Information). Here, CCDC25 is linked to hepatocellular carcinoma.