CD34 and acute myeloid leukemia: In the present study, we first evaluated the effects of digoxin, digitoxin analog D6-MA, and ouabain in various subtypes of human AML cells containing different proportions of LSCs, LPCs, and LBs in comparison to peripheral blood mononuclear cells (PBMCs) and CD34+ hematopoietic stem/progenitor cells (HSPCs) obtained from healthy donors.