In addition, [65], who reported that CEA, CA19-9 were high in benign gastric disease, these result was in agreement with many previous results which showed the correlation between H. pylori gastritis and levels of these tumor markers and compare the value of four tumor markers (CEA,CA72-4, CA19-9 and CA125) were increased in early GC. This evidence concerns the gene CEACAM5 and gastric cancer.