INS and Infertility: Among the 14,948 participants, we excluded 12,003 participants younger than 18 years or older than 36 years, 444 participants with missing infertility data, 1453 participants with missing BMI, triglyceride, serum insulin and fasting glucose data, and 5 participant who responded with “refused” or “unclear”, finally we included 1043 participants for the final analysis (Fig. 1).