CD274 and hepatocellular carcinoma: Given the relevance of DLAT to HCC immune infiltration, we also explored the correlation between DLAT and several immune checkpoint-related genes, revealing that DLAT was significantly and positively correlated with CD274, Cytotoxic T-Lymphocyte Associated Protein 4 (CTLA4), Hepatitis A Virus Cellular Receptor 2 (HAVCR2), Programmed Cell Death 1 Ligand 2 (PDCD1LG2) and T Cell Immunoreceptor With Ig And ITIM Domains (TIGIT) (Fig. 6E).