DAXX and acute promyelocytic leukemia: H3.3 is incorporated at telomeric regions coupled to histone H4 in nucleosomes exquisitely by Alpha-thalassaemia X-linked mental retardation (Atrx); Death domain-associated protein (Daxx) can also contribute to H3.3 deposition at telomeres recruiting a pool of non-nucleosomal H3.3 to Promyelocytic Leukaemia nuclear bodies prior to deposition [64].