First, PA treatment or PHF2 knockdown increased lipogenesis- and cell proliferation-related gene expressions in HCC cells (Fig. 7a and Supplementary Fig. 11a, columns 1–4), whereas SREBP1c knockdown abolished it (Fig. 7a and Supplementary Fig. 11a, columns 5–6). This evidence concerns the gene PHF2 and hepatocellular carcinoma.