KIT and amenorrhea: In our rhesus model post-ADC conditioning, the ovaries appeared normal at necropsy (ZJ10 in 0.3 mg/kg CD117-ADC and ZI07 in 0.6 mg/kg CD117-ADC), and all four female recipients continued menstruating after CD117-ADC conditioning, in contrast to the busulfan-conditioned recipients where amenorrhea is generally observed in humans31 and rhesus.