KRAS and neoplasm: To investigate the in vivo anti-tumor potency of 1-2C TCR-T cells, we subcutaneously engrafted PANC-1 cells stably expressing the KRAS-G12V mutant gene in a NOD-Prkdcem26Cd52Il2rgem26Cd22/NjuCrl (NCG) mouse model (Fig. 5a).