CD8A and neoplasm: However, single cell RNA sequencing (scRNAseq) of tumor-infiltrating lymphocytes from murine subcutaneous Panc02-H7-Fluc tumors revealed that PD1-IL2v treatment also increases the frequency of a population of ‘better effector’ T cells (CD8+ GZMB+ TIM-3− PD-1+ TCF7low/−) [8].