To assess whether the HOXD1, HOXD3, and HOXD4 overexpression in tumor tissues was related to cancer progression, the result showed that HOXD1 was markedly associated with different pathological stages of cancers, including KICH, KIRC, LIHC, THCA (p < 0.05) (Figure 2A). This evidence concerns the gene HOXD1 and cancer.