HOXD1 and rectum adenocarcinoma: However, the HOXD1 expression was decreased in BRCA (Breast invasive carcinoma), COAD (colon adenocarcinoma), KICH (Kidney chromophobe), KIRC, KIRP (Kidney renal papillary cell carcinoma), READ (Rectum adenocarcinoma), and TGCT (Testicular germ cell tumors) (p < 0.01) (Figure 1A).