TSHR and Graves ophthalmopathy: Using animal models established by immunization with human TSHR, Masetti et al. [74] and Moshkelgosha et al. [75] analyzed how differences in gut microbiota influence the clinical manifestation of GD and Graves’ ophthalmopathy (GO) with two experiments: the first one comparing the same mouse model (BALB/c mice) placed in two different locations (Germany, UK); the second one comparing two different mice strains (C57BL/6 and BALB/c mice).