SF3B1 and hepatocellular carcinoma: However, also in various solid tumors, SF3B1 is recurrently mutated, including uveal melanoma (UVM; Furney et al., 2013), breast cancer (BRCA; Fu et al., 2017; Maguire et al., 2015; Sun et al., 2020), prolactinomas (Li et al., 2020), hepatocellular carcinoma (HCC; Zhao et al., 2021), and pancreatic adenocarcinoma (PDAC; Bailey et al., 2016; Yang et al., 2021).