Qu et al18 reported that AKR1B10 was substantially upregulated in breast cancer tissues, and it facilitated cell malignant phenotypes via modulation of Phosphoinositide 3-kinase/Protein Kinase B/Nuclear factor kappa-B (PI3K/AKT/NF-κB) signaling pathway. The gene discussed is NFKB1; the disease is breast carcinoma.