Studies on albino rats demonstrated that lycopene prevented the risk of type 2 diabetes mellitus and attenuated diabetic neuropathy by preventing oxidative stress in pancreatic tissue by increasing SOD and GSH‐Px, lowering MDA levels, improving glycolipid metabolism by increasing serum HDL, insulin levels, lowering serum glucose, TG, TC, LDL, Gly‐LDL, cholesterol, and GHb level, and inhibiting TNF‐α and NO generation (Kuhad, Sharma, & Chopra, 2008; Yin et al., 2019). This evidence concerns the gene INS and diabetes mellitus.