Moreover, we found that CD3, CD247, CD2, and CD40LG were negatively correlated with KC, whereas MMP-9, LCN2, and RETN were positively correlated with KC (Figure 5B), suggesting that these candidate hub genes may regulate geriatric sepsis-induced ARDS by modulating the recruitment of neutrophils to the lung. This evidence concerns the gene CD40LG and Sepsis.