In the recent past, studies on several gut-related cancer types have documented the efficacy of a humanized anti- TLR2 antibody namely OPN-301 in suppressing the inflammation-driven tumorigenesis and proliferation of the gastric tumor cells in accordance with the downregulation of the expression of CXCL2 and TNF-α in murine model (303). Here, TLR2 is linked to cancer.