Bone morphogenic protein-7 (BMP7), E-cadherin (CDH1), N-cadherin (CDH2), Crohn’s disease (CD); Dextran sodium sulfate (DSS); Epithelial Growth factor (EGF); Fibroblast growth factor (FGF); Intestinal epithelial cell (IEC); Serine/arginine-rich splicing factor 1 (SRSF1); Transforming growth factor (TGF); Trinitrobenzene sulfonic acid (TNBS); Zinc-finger E-box-binding (ZEB). This evidence concerns the gene EGF and Cowden disease.