In IBD models, succinate and SUCNR1 are capable of triggering EMT through the WNT pathway in vitro and in vivo (in a heterotopic intestinal transplant model of fibrosis in SUCNR1−/− mice) (Ortiz-Masiá et al., 2020a) (Table 2). The gene discussed is SUCNR1; the disease is inflammatory bowel disease.