ALB and Cirrhosis: In systemic circulation, they are bound mainly to albumin and lipoproteins, and are therefore found in the serum fraction larger than 30 kD.[144], [145], [146] Furthermore, serum bile acids are highly elevated in liver diseases, including cirrhosis,[147], [148], [149], [150], [151], [152], [153] which makes them a potential player in the regulation of neutrophil function in cirrhosis.