It is well known that HDL-c had a protective effect to prevent the development of atherosclerosis by inhibiting the expression of adhesion molecules (ICAM-1, VCAM-1 and E-selectin) induced by cytokines on the cell surface and also acts as antioxidant and mitogen and also binds the lipopolysaccharide [35]. Here, ICAM1 is linked to atherosclerosis.