CD47 and neoplasm: Notably, the inhibition of CD47 signaling is an efficacious strategy, underscored by the recent emergence of several CD47-targeting agents entering clinical trials [63] Another noteworthy "Don't eat me" signal stems from CD24, which interacts with the inhibitory receptor known as sialic acid-binding Ig-like lectin 10 (Siglec-10) on tumor-associated macrophages (TAMs).