Genetic analysis confirmed heterozygous pathogenic variants in both the <i>FOXC1</i> and <i>COL2A1</i> genes, leading to the concurrent diagnoses of Axenfeld-Rieger and Stickler syndromes.<h4>Conclusions and importance</h4>This is a rare case of a patient with concurrent Axenfeld-Rieger and Stickler syndromes. The gene discussed is FOXC1; the disease is Stickler syndrome.