Chemo‐ and radiotherapy can cause a shift in phenotype from PN‐GBM to MES‐GBM, resulting in resistance to those therapies.[23] We have previously demonstrated that FoxM1 and CD44 are upregulated by temozolomide (TMZ) in GBM cells.[23b] To determine whether the FBXO7‐Rbfox2 axis is involved in this process, we detected their expression in TMZ‐treated GSC1209 and GSC0709 cells. Here, RBFOX2 is linked to glioblastoma.