However, depletion of FBXO7 in GSCs abrogated tumor formation (Figure 1F), and substantially improved the survival of mice harboring GSC1023‐GBM tumors (median survival duration of 31 days for sh‐Ctrl versus 46 days for FBXO7‐sh1 & FBXO7‐sh2) and GSC0910‐GBM tumors (34d for sh‐Ctrl versus 57d & 62d for FBXO7‐sh1 & FBXO7‐sh2, respectively) (Figure 1G). This evidence concerns the gene FBXO7 and neoplasm.