Among the AS genes regulated by Rbfox2, we focused on FoxM1, Mta1 (metastatic tumor antigen 1) and Postn (Periostin), which are closely associated with MES properties and tumor progression.[2, 18, 19] The potential Rbfox2 binding motifs in these pre‐mRNAs are all located downstream of the spliced exons, resulting in exon inclusion (Figure 5D,E). This evidence concerns the gene RBFOX2 and neoplasm.