LIN28B and colonic neoplasm: LIN28B is an RNA binding protein (RBP) and is associated with RNA splicing, localization, stability, degradation, and translation by binding to the mRNA or microRNA of target genes.[42, 57, 58] Moreover, LIN28B is known to promote the development of neuroblastoma and colon cancer, among other neoplasias.[59, 60] One possible therapeutic strategy is LIN28B inhibition, although there are no such approved drugs to date.