Furthermore, we verified that the expression of FANCD2 was higher in Hepatitis B-related HCC than in normal tissues in GSE121248 (P = 5.9e−10), GSE55092 (P = 0.0021), GSE19665 (P = 1.1e−05) and GSE84402(P = 0.00034). This evidence concerns the gene FANCD2 and hepatitis B virus infection.