Judging from the results of the univariate analysis above, binary logistic regression analysis was performed with age, education level, severity of dependence, the presence of brain infarction and dementia, globulin (Glb), albumin (Alb), A/G, triiodothyronine (T3), free triiodothyronine (fT3), D-dimer (D-Di), fibrinogen degradation products (FDP), thrombin time (TT), HCY, creatine kinase (CK) as independent variables and the incidence of cognitive impairment as the dependent variable. This evidence concerns the gene ALB and Cognitive impairment.