FOXA1 and FOXH1 are members of FOX family of transcription factors, FOXA1 is decreased in hepatocellular carcinoma [46], FOXH1 promotes cell proliferation, invasion and tumorigenesis by enhancing the Wnt/β-catenin pathway in lung cancer cells and tissues [47]. The gene discussed is FOXA1; the disease is hepatocellular carcinoma.