20 cases of VASH2 were positive and negative in 29 cases of SHH-type medulloblastoma, with a positive rate of 68.97%, and VASH2 was positive in 3 cases and negative in 7 cases of 10 cases of non-SHH/WNT-type medulloblastoma, a positive rate of 30%. The gene discussed is SHH; the disease is medulloblastoma.