Compared to healthy donors, the proportion of plasmablasts (median log2 fold change: +1.7), CD14+ monocytes (+0.51), and proliferating CD4+ T cells (+1.7) subsets were increased, while the proportion of CD8+ naïve T cells (median log2 fold change: −1.2), MAIT cells (−2.5), gdT cells (−0.98), cDC1 (−1.6), cDC2 (−1.6), and ASDC (−3.4) subsets were decreased in patients with MPA (Fig. 1f). The gene discussed is CD8A; the disease is microscopic polyangiitis.