IFNG and breast neoplasm: Further, in support of our findings that emodin increases expression of select M1 macrophage markers (IFNγ and TNF) in wounded mice, M1 macrophages and their associated cytokines in the tumor‐associated environment (TME) have been consistently associated with reduced breast tumor burden and aggressiveness given their tumoricidal functions (Munir et al., 2021).