To explore a role for circTET2 in CLL, we conducted gene set enrichment analysis (GESA) of circTET2‐associated genes, and our results revealed that circTET2 was involved in the PI3K‐AKT pathway (Figure 5A) and mTORC1 signaling (Figure 5B), as well as in lipid metabolism (Figure 5C). This evidence concerns the gene AKT1 and B-cell chronic lymphocytic leukemia.