As expected, the expression of SLC7A11 was enhanced and miR-144-3p expression was reduced in the renal tissues of UTI-treated mice compared with that in LPS group (Fig. 5A, B). As shown in Fig. 5C, after UTI treatment, urine protein (24 h) was significantly decreased compared with the LPS group (P < 0.05). The gene discussed is SLC7A11; the disease is bacterial urinary tract infection.