Importantly, our results confirmed the upregulation of NAT10 protein expression in CCa specimens (Figure 1a), and this aberrant upregulation was associated with less favorable clinicopathological characteristics, such as high tumor stage (P<0.05) (Figure 1b) and lymph node metastasis (P<0.05), in CCa (Figure 1c). Here, NAT10 is linked to neoplasm.