Because more than 90% of CCa cases are due to infection with high‐risk HPV types, we utilized Integrated Genomics Viewer (IGV) to identify signals indicating accessible chromatin surrounding the transcription start site (TSS) of NAT10 and aimed to define TF candidates at regions of accessible chromatin in HFF‐1 (noncancerous control), H8 (noncancerous with HPV16 E6 and E7) and SiHa (CCa cells with HPV16 E6 and E7) cells (Figure 2b). This evidence concerns the gene TF and infection.