showed that NAT10 can regulate the ac4C level of COL5A1 mRNA through a direct interaction to accelerate epithelial–mesenchymal transition and metastasis of gastric cancer cells.[20] Despite accumulating evidence demonstrating the effect of NAT10 on cancer development, the functional importance of the ac4C writer NAT10 in CCa remains an open area of investigation. Here, NAT10 is linked to gastric cancer.