TNF-α: Tumor Necrosis Factor-alpha (infliximab and adalimumab); JAK-STAT: Janus kinase/Signalling transducer of activators of transcription (ruxolitinib and tofacitinib); CS: Cutaneous sarcoidosis; CSAMI: Cutaneous Sarcoidosis Activity and Morphology Instrument. The gene discussed is SOAT1; the disease is skin sarcoidosis.