Using EAE as a rat model of MS, it was shown that 12 days after the inoculation of myelin basic protein (MBP), CX3CL1 and CX3CR1 mRNA and protein levels were increased in dorsal root ganglia (DRG) and spinal cord (Zhu et al., 2013). The gene discussed is MBP; the disease is myeloid sarcoma.