The number size of normal tissues in the TCGA database is too small to be statistically convincing (e.g., the numbers of normal controls in GBM and LGG cohorts were 5 and 0, respectively), we therefore matched the normal tissues and cancer samples from GTEx and TCGA to reflect the PLEKHA4 expression in a more convincing manner. This evidence concerns the gene PLEKHA4 and glioblastoma.