PLEKHA4 and colon adenocarcinoma: As shown in Figure 1A, elevated PLEKHA4 expression was observed in various cancer types, including cholangio carcinoma (CHOL), colon adenocarcinoma (COAD), glioblastoma multiforme (GBM), kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), stomach adenocarcinoma (STAD), and thyroid carcinoma (THCA).