Furthermore, to determine the predictive power of PLEKHA4, ROC curves were constructed and the AUCs for LGG and GBM were 0.844 (95% CI=0.824-0.864) and 0.977 (95% CI=0.970-0.985), respectively (Figure 2G), suggesting that PLEKHA4 is an effective index for the diagnosis of LGG or GBM patients. The gene discussed is PLEKHA4; the disease is glioblastoma.