ADGRB1 and colitis: Inhibition of IEC phagocytosis by genetic ablation of the phagocytic receptor BAI1 in IEC resulted in worsened DSS colitis with many uncleared apoptotic corpses and inflammatory cytokines within the colonic epithelium (51). A forced overexpression of BAI1 resulted in fewer apoptotic cells, reduced inflammation, and attenuated disease (51).