Therefore, the CDC recommends that RRC aged 2–14 from endemic or high-burden disease countries (i.e., countries with TB incidence rate of ≥20 cases per 100,000 population) should be screened with an interferon-gamma release assay (IGRA) blood test (20), while adolescents over 15 years old should be screened with chest radiographs (17). Here, IFNG is linked to tuberculosis.