Shen et al.’s study (Shen et al., 2023) posits that the Leonurine alkaloid can mitigate lung cancer through the NF-κB signaling pathway, decrease phosphorylation and nuclear translocation in myocardial cells’ P65, and subsequently attenuate the expression of inflammatory factors such as IL-6, TNF-α, and MCP-1. The gene discussed is NFKB1; the disease is lung cancer.