BCL2 and neuroblastoma: Salvigenin, a known polyphenol flavonoid, also shown to be present in BLS WIE, inhibits hydrogen peroxide-induced apoptosis, reduces the generation of ROS and reduces caspase-3 levels as well as Bax/Bcl-2 ratio in SH-Sy5Y neuroblastoma cells (Rafatian et al., 2012).